BDBM50110778 2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-(2-iodo-vinyl)-phenylamine::CHEMBL277045

SMILES CN(C)Cc1ccccc1Sc1ccc(\C=C\I)cc1N

InChI Key InChIKey=JAURUKPBSNINJP-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50110778   

TargetSodium-dependent serotonin transporter(Rat)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50110778(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-(2-iodo...)
Affinity DataKi:  53.3nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transporter (SERT) of rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50110778(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-(2-iodo...)
Affinity DataKi:  80.2nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine transporter (NET) of rat cortical homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50110778(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-(2-iodo...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]-GBR-12,935 binding to dopamine transporter (DAT) of rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed