BDBM50111032 2,2-Dimethyl-propionic acid 9-[1-thiophen-2-yl-meth-(Z)-ylidene]-7-aza-tricyclo[4.3.1.0*3,7*]dec-2-ylmethyl ester::CHEMBL173834

SMILES CC(C)(C)C(=O)OCC1C2CCC3CC1\C(CN23)=C\c1cccs1

InChI Key InChIKey=SHHWJFWQYLCSAZ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50111032   

TargetSodium-dependent serotonin transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50111032(2,2-Dimethyl-propionic acid 9-[1-thiophen-2-yl-met...)
Affinity DataKi:  168nMAssay Description:Inhibition of [3H]5-HT reuptake at serotonin transporter in rat mid brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50111032(2,2-Dimethyl-propionic acid 9-[1-thiophen-2-yl-met...)
Affinity DataKi:  1.02E+3nMAssay Description:Inhibition of [3H]DA reuptake at dopamine transporter in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50111032(2,2-Dimethyl-propionic acid 9-[1-thiophen-2-yl-met...)
Affinity DataKi:  1.18E+3nMAssay Description:Inhibition of [3H]-NE reuptake at Norepinephrine transporter in rat parietal/occipital cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed