BDBM50111321 CHEMBL10763::N'-(11-Methoxy-13H-5,13-diaza-dibenzo[a,i]fluoren-6-yl)-N,N-dimethyl-ethane-1,2-diamine

SMILES COc1ccc2ccc3c([nH]c4c3c(NCCN(C)C)nc3ccccc43)c2c1

InChI Key InChIKey=GOCZKPDHVLYWBI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50111321   

TargetDNA polymerase I, thermostable(Thermus aquaticus)
National Museum of Natural History

Curated by ChEMBL
LigandPNGBDBM50111321(N'-(11-Methoxy-13H-5,13-diaza-dibenzo[a,i]fluoren-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Tested for inhibitory activity against Taq DNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
National Museum of Natural History

Curated by ChEMBL
LigandPNGBDBM50111321(N'-(11-Methoxy-13H-5,13-diaza-dibenzo[a,i]fluoren-...)
Affinity DataIC50: 9.80E+3nMAssay Description:Tested for inhibitory activity against Telomerase in telomerase repeat amplification protocol (TRAP) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
National Museum of Natural History

Curated by ChEMBL
LigandPNGBDBM50111321(N'-(11-Methoxy-13H-5,13-diaza-dibenzo[a,i]fluoren-...)
Affinity DataIC50: 1.26E+9nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article