BDBM50111446 5-Chloro-naphthalene-1-sulfonic acid (6-amino-hexyl)-amide::CHEMBL41631::N-(6-AMINOHEXYL)-5-CHLORO-1-NAPHTHALENESULFONAMIDE::N-(6-aminohexyl)-5-chloronaphthalene-1-sulfonamide

SMILES c1cc2c(cccc2Cl)c(c1)S(=O)(=O)NCCCCCCN

InChI Key InChIKey=IDEHCMNLNCJQST-UHFFFAOYSA-N

Data  1 KI  3 IC50  2 Kd  1 EC50

PDB links: 4 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50111446   

TargetCalmodulin(Bovine)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50111446(N-(6-AMINOHEXYL)-5-CHLORO-1-NAPHTHALENESULFONAMIDE...)
Affinity DataKd:  1.20E+4nMAssay Description:Binding affinity to bovine brain CaM by FTPFACE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2017
Entry Details Article
PubMed
TargetCalmodulin(Bovine)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50111446(N-(6-AMINOHEXYL)-5-CHLORO-1-NAPHTHALENESULFONAMIDE...)
Affinity DataKd:  7.20E+3nMAssay Description:Binding affinity to dansylated bovine testes CaM by fluorescence analysis in presence of calcium2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2017
Entry Details Article
PubMed
TargetCalmodulin(Bovine)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50111446(N-(6-AMINOHEXYL)-5-CHLORO-1-NAPHTHALENESULFONAMIDE...)
Affinity DataIC50: 1.36E+4nMAssay Description:Displacement of [3H] ifenprodil from bovine CaM-agarose incubated for 30 mins by liquid scintillation spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2017
Entry Details Article
PubMed
TargetCalmodulin(Bovine)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50111446(N-(6-AMINOHEXYL)-5-CHLORO-1-NAPHTHALENESULFONAMIDE...)
Affinity DataEC50:  7.20E+3nMAssay Description:Binding affinity to dansylated bovine brain CaM assessed as half maximal increase in fluorescence by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2017
Entry Details Article
PubMed
TargetMO15-related protein kinase Pfmrk(malaria parasite P. falciparum)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50111446(N-(6-AMINOHEXYL)-5-CHLORO-1-NAPHTHALENESULFONAMIDE...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of Plasmodium falciparum PfmrkMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50111446(N-(6-AMINOHEXYL)-5-CHLORO-1-NAPHTHALENESULFONAMIDE...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2018
Entry Details Article
PubMed
TargetMyosin light chain kinase, smooth muscle(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50111446(N-(6-AMINOHEXYL)-5-CHLORO-1-NAPHTHALENESULFONAMIDE...)
Affinity DataKi:  1.10E+5nMAssay Description:Inhibition of MLCK by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed