BDBM50111882 (E)-5-Iodo-1-(8-methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]oct-2-yl)-pent-4-en-1-one::CHEMBL169320

SMILES CN1C2CCC1C(C(C2)c1ccc(C)cc1)C(=O)CC\C=C\I

InChI Key InChIKey=WPOWYXAYIRKXTG-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50111882   

TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50111882((E)-5-Iodo-1-(8-methyl-3-p-tolyl-8-aza-bicyclo[3.2...)
Affinity DataIC50: 13nMAssay Description:Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50111882((E)-5-Iodo-1-(8-methyl-3-p-tolyl-8-aza-bicyclo[3.2...)
Affinity DataKi:  51nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed