BDBM50111906 (S)-1-[(S)-2-{2-[(R)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-(2,6-dimethyl-phenyl)-propionylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid ((S)-1-carbamoyl-2-hydroxy-ethyl)-amide::CHEMBL168110

SMILES C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c(C)cccc1C)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(N)=O

InChI Key InChIKey=OJIZXSLNRWQEAY-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50111906   

TargetMu-type opioid receptor(Guinea pig)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50111906((S)-1-[(S)-2-{2-[(R)-2-{(R)-2-[(S)-2-Amino-3-(4-hy...)
Affinity DataIC50: 44nMAssay Description:In vitro biological activity by electrically induced smooth muscle contractions in guinea pig ileum (Opioid receptor mu 1); inhibitory concentration ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50111906((S)-1-[(S)-2-{2-[(R)-2-{(R)-2-[(S)-2-Amino-3-(4-hy...)
Affinity DataIC50: 358nMAssay Description:In vitro biological activity by electrically induced smooth muscle contractions in mouse vas deferens (Opioid receptor delta 1); inhibitory concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50111906((S)-1-[(S)-2-{2-[(R)-2-{(R)-2-[(S)-2-Amino-3-(4-hy...)
Affinity DataKi:  4.40nMAssay Description:Binding affinity against Opioid receptor mu 1 using [3H]DAMGO in rat brain synaptosomes was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50111906((S)-1-[(S)-2-{2-[(R)-2-{(R)-2-[(S)-2-Amino-3-(4-hy...)
Affinity DataKi:  3.30E+3nMAssay Description:Binding affinity against Opioid receptor delta 1 using [3H]DT in rat brain synaptosomes was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed