BDBM50112073 CHEMBL417360::[{2-[2-(4-Carbamimidoyl-phenyl)-ethyl]-1-methyl-1H-benzoimidazol-5-yl}-(quinoline-8-sulfonyl)-amino]-acetic acid

SMILES Cn1c(CCc2ccc(cc2)C(N)=N)nc2cc(ccc12)N(CC(O)=O)S(=O)(=O)c1cccc2cccnc12

InChI Key InChIKey=AUMKTQJOSFGRPC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50112073   

TargetProthrombin(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50112073([{2-[2-(4-Carbamimidoyl-phenyl)-ethyl]-1-methyl-1H...)
Affinity DataIC50: 32nMAssay Description:Inhibition of human thrombin by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50112073([{2-[2-(4-Carbamimidoyl-phenyl)-ethyl]-1-methyl-1H...)
Affinity DataIC50: 32nMAssay Description:Inhibition of human thrombin using tosyl-glycyl-prolyl-arginine-4-nitranilide acetate as substrate preincubated for 10 mins followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed