BDBM50112315 CHEMBL3609299

SMILES CC[C@H]1N(C2CCCC2)c2nc(Nc3ccc(cc3OC)C(=O)NC3CCN(C)CC3)ncc2NC1=O

InChI Key InChIKey=ZUABLHLALIWUPH-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50112315   

TargetBromodomain-containing protein 4(Human)
Dana Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50112315(CHEMBL3609299)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of Bio-JQ1 from recombinant human His6 tagged BRD4 bromodomain 1 by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetTranscription initiation factor TFIID subunit 1(Human)
Dana Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50112315(CHEMBL3609299)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of biotinylated probe from human TAF1 bromodomain 2 (1522 to 1656 residues) expressed in Escherichia coli BL21 (DE3) by alphascreen assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Dana Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50112315(CHEMBL3609299)
Affinity DataKi:  7.95E+3nMAssay Description:Binding affinity to BRD4 (unknown origin) expressed in Escherichia coli BL21 after 1 hr by proprietary competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2016
Entry Details Article
PubMed