BDBM50112328 3-[Bis-(4-fluoro-phenyl)-methoxy]-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid benzyl ester::CHEMBL283154

SMILES CN1C2CCC1C(C(C2)OC(c1ccc(F)cc1)c1ccc(F)cc1)C(=O)OCc1ccccc1

InChI Key

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50112328   

TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50112328(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-methyl-8-aza-b...)
Affinity DataKi:  40nMAssay Description:Ability to displace [3H]WIN-35 radioligand for the dopamine transporter 428 DAT in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50112328(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-methyl-8-aza-b...)
Affinity DataKi:  90nMAssay Description:Ability to displace [3H]WIN-35 radioligand for the dopamine transporter 428 DAT in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50112328(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-methyl-8-aza-b...)
Affinity DataKi:  2.04E+3nMAssay Description:Ability to displace [3H]citalopram radioligand, for the Serotonin transporter in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50112328(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-methyl-8-aza-b...)
Affinity DataKi:  2.04E+3nMAssay Description:Ability to displace [3H]citalopram radioligand, for the Serotonin transporter in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50112328(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-methyl-8-aza-b...)
Affinity DataKi:  2.23E+3nMAssay Description:Ability to displace [3H]-nisoxatine radioligand for the Norepinephrine transporter in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50112328(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-methyl-8-aza-b...)
Affinity DataKi:  2.23E+3nMAssay Description:Ability to displace [3H]-nisoxatine radioligand for the Norepinephrine transporter in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50112328(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-methyl-8-aza-b...)
Affinity DataKi:  4.38E+3nMAssay Description:Ability to displace [3H]pirenzepine radioligand for the Muscarinic acetylcholine receptor M1 in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50112328(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-methyl-8-aza-b...)
Affinity DataKi:  4.38E+3nMAssay Description:Ability to displace [3H]pirenzepine radioligand for the Muscarinic acetylcholine receptor M1 in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed