BDBM50112330 3-[Bis-(4-fluoro-phenyl)-methoxy]-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid ethyl ester::CHEMBL281388

SMILES CCOC(=O)C1C2CCC(CC1OC(c1ccc(F)cc1)c1ccc(F)cc1)N2C

InChI Key

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50112330   

TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50112330(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-methyl-8-aza-b...)
Affinity DataKi:  16.8nMAssay Description:Ability to displace [3H]WIN-35 radioligand for the dopamine transporter 428 DAT in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50112330(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-methyl-8-aza-b...)
Affinity DataKi:  17nMAssay Description:Ability to displace [3H]WIN-35 radioligand for the dopamine transporter 428 DAT in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50112330(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-methyl-8-aza-b...)
Affinity DataKi:  1.02E+3nMAssay Description:Ability to displace [3H]-nisoxatine radioligand for the Norepinephrine transporter in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50112330(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-methyl-8-aza-b...)
Affinity DataKi:  1.02E+3nMAssay Description:Ability to displace [3H]-nisoxatine radioligand for the Norepinephrine transporter in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50112330(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-methyl-8-aza-b...)
Affinity DataKi:  1.86E+3nMAssay Description:Ability to displace [3H]pirenzepine radioligand for the Muscarinic acetylcholine receptor M1 in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50112330(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-methyl-8-aza-b...)
Affinity DataKi:  1.89E+3nMAssay Description:Ability to displace [3H]pirenzepine radioligand for the Muscarinic acetylcholine receptor M1 in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50112330(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-methyl-8-aza-b...)
Affinity DataKi:  3.74E+3nMAssay Description:Ability to displace [3H]citalopram radioligand, for the Serotonin transporter in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50112330(3-[Bis-(4-fluoro-phenyl)-methoxy]-8-methyl-8-aza-b...)
Affinity DataKi:  3.74E+3nMAssay Description:Ability to displace [3H]citalopram radioligand, for the Serotonin transporter in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed