BDBM50112496 CHEMBL26709::N-[3-(5-Carbamimidoyl-2-hydroxy-phenyl)-allyl]-N-[4-(1-carboxymethyl-piperidin-4-yloxy)-3-trifluoromethyl-phenyl]-succinamic acid

SMILES NC(=N)c1ccc(O)c(\C=C\CN(C(=O)CCC(O)=O)c2ccc(OC3CCN(CC(O)=O)CC3)c(c2)C(F)(F)F)c1

InChI Key InChIKey=DROPCIKBXHBPQC-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50112496   

TargetCoagulation factor X(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50112496(N-[3-(5-Carbamimidoyl-2-hydroxy-phenyl)-allyl]-N-[...)
Affinity DataKi:  0.340nMAssay Description:Competitive inhibition of coagulation factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50112496(N-[3-(5-Carbamimidoyl-2-hydroxy-phenyl)-allyl]-N-[...)
Affinity DataKi:  870nMAssay Description:Competitive inhibition of trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50112496(N-[3-(5-Carbamimidoyl-2-hydroxy-phenyl)-allyl]-N-[...)
Affinity DataKi: >5.00E+3nMAssay Description:Competitive inhibition of coagulation factor IIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed