BDBM50113331 (4-Fluoro-phenyl)-{1-[2-(2-iodo-phenyl)-ethyl]-piperidin-4-yl}-methanone::CHEMBL74756

SMILES Fc1ccc(cc1)C(=O)C1CCN(CCc2ccccc2I)CC1

InChI Key InChIKey=JREBTSVEMYTHEU-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50113331   

TargetD(2) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50113331((4-Fluoro-phenyl)-{1-[2-(2-iodo-phenyl)-ethyl]-pip...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity (Ki) at Dopamine receptor D2 using rat caudate cells with nemonapride (0.075 nM) as a radioligand and 10 M haloperidol as a blank ag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50113331((4-Fluoro-phenyl)-{1-[2-(2-iodo-phenyl)-ethyl]-pip...)
Affinity DataKi:  1.95nMAssay Description:Tested on genetically transfected COS7 cell membranes selectively expressing human 5-hydroxytryptamine 2A receptor, using [3H]ketanserin as radioliga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50113331((4-Fluoro-phenyl)-{1-[2-(2-iodo-phenyl)-ethyl]-pip...)
Affinity DataKi:  3.68nMAssay Description:Tested on cell membranes from transfected cells selectively expressing human 5-hydroxytryptamine 7 receptor incubated with 1 nM [3H]LSDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50113331((4-Fluoro-phenyl)-{1-[2-(2-iodo-phenyl)-ethyl]-pip...)
Affinity DataKi:  35.5nMAssay Description:Tested on transfected cell membranes selectively expressing human 5-hydroxytryptamine 2C receptor using [3H]mesulergineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50113331((4-Fluoro-phenyl)-{1-[2-(2-iodo-phenyl)-ethyl]-pip...)
Affinity DataKi:  138nMAssay Description:Tested on cell membranes from transfected cells selectively expressing human 5-hydroxytryptamine 6 receptor incubated with 1 nM [3H]LSDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed