BDBM50113341 CHEMBL3603907

SMILES Fc1cc(cc(c1)-c1cc(ncn1)-n1cccn1)C#N

InChI Key InChIKey=NCHHUFRUEZCIEJ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50113341   

TargetMetabotropic glutamate receptor 5(Human)
Heptares Therapeutics

Curated by ChEMBL
LigandPNGBDBM50113341(CHEMBL3603907)
Affinity DataIC50: 398nMAssay Description:Negative allosteric modulation at human mGlu5 receptor expressed in HEK293 cells assessed as inhibition of L-quisqualic acid-induced inositol phospha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Heptares Therapeutics

Curated by ChEMBL
LigandPNGBDBM50113341(CHEMBL3603907)
Affinity DataKi:  63nMAssay Description:Displacement of [3H]-M-MPEP from human mGlu5 receptor expressed in HEK293 cells after 90 mins by scintillation spectroscopy analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details Article
PubMed