BDBM50113460 CHEMBL3606013::US11420940, cpd (16)

SMILES NC(=O)c1cccc2CN(C3CCN(Cc4ccc[nH]4)CC3)C(=O)c12

InChI Key InChIKey=RRKFGRBPRSLJIT-UHFFFAOYSA-N

Data  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50113460   

TargetPoly [ADP-ribose] polymerase 1(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50113460(CHEMBL3606013 | US11420940, cpd (16))
Affinity DataKd: <30nMAssay Description:Binding affinity to full length recombinant human PARP-1 by fluorescence polarization displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50113460(CHEMBL3606013 | US11420940, cpd (16))
Affinity DataKd: <30nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM50113460(CHEMBL3606013 | US11420940, cpd (16))
Affinity DataKd:  980nMAssay Description:The assay is based on the use of a probe of formula (IP) that binds to the NAD binding pocket and takes advantage of the significant change in the po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM50113460(CHEMBL3606013 | US11420940, cpd (16))
Affinity DataKd:  983nMAssay Description:Binding affinity to full length recombinant human PARP-2 by fluorescence polarization displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2016
Entry Details Article
PubMed