BDBM50114032 CHEMBL86577::{4-[2-(3-Biphenyl-4-yl-5-methyl-[1,2,4]triazol-4-yl)-phenoxymethyl]-phenyl}-(4-methyl-piperazin-1-yl)-methanone

SMILES CN1CCN(CC1)C(=O)c1ccc(COc2ccccc2-n2c(C)nnc2-c2ccc(cc2)-c2ccccc2)cc1

InChI Key InChIKey=MEDYXWWEPBZLAH-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50114032   

TargetVasopressin V1a receptor(Human)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50114032({4-[2-(3-Biphenyl-4-yl-5-methyl-[1,2,4]triazol-4-y...)
Affinity DataKi:  3.03nMAssay Description:Binding affinity at cloned human Vasopressin V1a receptor stably expressed in CHO cells, using [3H]AVP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Rat)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50114032({4-[2-(3-Biphenyl-4-yl-5-methyl-[1,2,4]triazol-4-y...)
Affinity DataKi:  62.7nMAssay Description:Binding affinity at Vasopressin V1a receptor, performed using [3H]AVP on rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Rat)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50114032({4-[2-(3-Biphenyl-4-yl-5-methyl-[1,2,4]triazol-4-y...)
Affinity DataKi:  364nMAssay Description:Binding affinity at Vasopressin V2 receptor, performed using [3H]AVP on rat kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50114032({4-[2-(3-Biphenyl-4-yl-5-methyl-[1,2,4]triazol-4-y...)
Affinity DataKi:  585nMAssay Description:Binding affinity at cloned human Vasopressin V2 receptor stably expressed in CHO cells, using [3H]AVP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed