BDBM50114047 CHEMBL3605409

SMILES Nc1cc(Cl)ccc1C(=O)NC1(CCCCC1)C(=O)NCC#N

InChI Key InChIKey=YIZGSWYIXVMETJ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50114047   

TargetCathepsin K(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50114047(CHEMBL3605409)
Affinity DataKi:  16nMAssay Description:Inhibition of human cathepsin-K using Z-Gly-Pro-Arg-AMC as substrate preincubated for 30 mins measured after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed
TargetProcathepsin L(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50114047(CHEMBL3605409)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of human cathepsin-L using Z-Phe-Arg-AMC as substrate preincubated for 30 mins measured after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2016
Entry Details Article
PubMed