BDBM50114290 (S)-2-(4,6-Dimethoxy-[1,3,5]triazin-2-ylamino)-3-[4-(2-fluoro-6-trifluoromethyl-benzoylamino)-phenyl]-propionic acid::CHEMBL41745

SMILES COc1nc(N[C@@H](Cc2ccc(NC(=O)c3c(F)cccc3C(F)(F)F)cc2)C(O)=O)nc(OC)n1

InChI Key InChIKey=UFPHSDSUWFUDFC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50114290   

TargetIntegrin alpha-4/beta-1(Human)
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114290((S)-2-(4,6-Dimethoxy-[1,3,5]triazin-2-ylamino)-3-[...)
Affinity DataIC50: 50nMAssay Description:Inhibition of VLA-4 from HL60 lysate in a protein-based ligand binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114290((S)-2-(4,6-Dimethoxy-[1,3,5]triazin-2-ylamino)-3-[...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of VLA-4 expressed in Jurkat cell line, in a cell-based adhesion assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed