BDBM50114416 CHEMBL3608351

SMILES COc1ccc(cc1)-c1nnc(Cn2nc(-c3ccccc3)c(nc2=O)-c2ccccc2)o1

InChI Key InChIKey=BLDMCAJCUTWQRV-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50114416   

TargetProstaglandin G/H synthase 2(Sheep)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandPNGBDBM50114416(CHEMBL3608351)
Affinity DataIC50: 3.23E+3nMAssay Description:Inhibition of ovine COX2 by oxidized TMPD detection based colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandPNGBDBM50114416(CHEMBL3608351)
Affinity DataKi:  1.48E+4nMAssay Description:Competitive inhibition of ovine COX2 using arachidonic acid substrate by Ellman's spectrophotometric assay based Lineweaver-Burk double reciprocal pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandPNGBDBM50114416(CHEMBL3608351)
Affinity DataIC50: 4.49E+4nMAssay Description:Inhibition of ovine COX1 by oxidized TMPD detection based colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed