BDBM50114917 (3R,5S)-5-[4-(4-Fluoro-benzyl)-5-methylsulfanyl-4H-[1,2,4]triazol-3-yl]-1-(naphthalene-2-sulfonyl)-pyrrolidine-3-thiol::CHEMBL299074

SMILES CSc1nnc([C@@H]2C[C@@H](S)CN2S(=O)(=O)c2ccc3ccccc3c2)n1Cc1ccc(F)cc1

InChI Key InChIKey=WAUPDZJGGBCBAR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50114917   

TargetEndothelin-converting enzyme 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50114917((3R,5S)-5-[4-(4-Fluoro-benzyl)-5-methylsulfanyl-4H...)
Affinity DataIC50: 150nMAssay Description:Tested for inhibitory concentration against human Endothelin-converting enzyme 1 at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed