BDBM50115023 1-(3-Acetyl-phenyl)-3-{3-[4-(4-fluoro-benzyl)-piperidin-1-yl]-propyl}-urea::CHEMBL295832

SMILES CC(=O)c1cccc(NC(=O)NCCCN2CCC(Cc3ccc(F)cc3)CC2)c1

InChI Key InChIKey=JSUGTZOUOKXRQN-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50115023   

TargetC-C chemokine receptor type 3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50115023(1-(3-Acetyl-phenyl)-3-{3-[4-(4-fluoro-benzyl)-pipe...)
Affinity DataIC50: 10nMAssay Description:In vitro C-C chemokine receptor type 3 activity of compound by using eotaxin induced human eosinophil chemotaxis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50115023(1-(3-Acetyl-phenyl)-3-{3-[4-(4-fluoro-benzyl)-pipe...)
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against C-C chemokine receptor type 3 using human [125I]eotaxin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50115023(1-(3-Acetyl-phenyl)-3-{3-[4-(4-fluoro-benzyl)-pipe...)
Affinity DataIC50: 10nMAssay Description:Inhibition of eotaxin-induced chemotaxis of human eosinophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50115023(1-(3-Acetyl-phenyl)-3-{3-[4-(4-fluoro-benzyl)-pipe...)
Affinity DataKi:  193nMAssay Description:Inhibition of [125I]-eotaxin binding to serotonin 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed