BDBM50115395 CHEMBL3608460

SMILES OC[C@@H](N1CCCn2cc(cc2C1=O)-c1ccnc(N[C@H]2CC[C@@H](O)C2)n1)c1ccccc1

InChI Key InChIKey=BJEBSDJGFJFHTM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50115395   

TargetMitogen-activated protein kinase 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50115395(CHEMBL3608460)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50115395(CHEMBL3608460)
Affinity DataIC50: 278nMAssay Description:Inhibition of ERK2 in human A375 cells assessed as phosphorylated FRA levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2016
Entry Details Article
PubMed