BDBM50115573 3-Hydroxy-1-(1H-indol-3-yl)-3-(1H-tetrazol-5-yl)-propenone::CHEMBL320040

SMILES O=C(CC(=O)c1c[nH]c2ccccc12)c1nnn[nH]1

InChI Key InChIKey=MDDSGQRWLCNBFO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50115573   

TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute/Nih

Curated by ChEMBL
LigandPNGBDBM50115573(3-Hydroxy-1-(1H-indol-3-yl)-3-(1H-tetrazol-5-yl)-p...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibitory effect on strand transfer of proximal DNA into host DNA in an extracellular HIV-1 integrase assay in experiment 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute/Nih

Curated by ChEMBL
LigandPNGBDBM50115573(3-Hydroxy-1-(1H-indol-3-yl)-3-(1H-tetrazol-5-yl)-p...)
Affinity DataIC50: 1.95E+3nMAssay Description:Strand transfer inhibitory activity against HIV-1 integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute/Nih

Curated by ChEMBL
LigandPNGBDBM50115573(3-Hydroxy-1-(1H-indol-3-yl)-3-(1H-tetrazol-5-yl)-p...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory effect on strand transfer of proximal DNA into host DNA in an extracellular HIV-1 integrase assay in experiment 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute/Nih

Curated by ChEMBL
LigandPNGBDBM50115573(3-Hydroxy-1-(1H-indol-3-yl)-3-(1H-tetrazol-5-yl)-p...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory effect on 3'-processing(3'-P) of proximal DNA in an extracellular HIV-1 integrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed