BDBM50115854 6-Fluoro-2-[2-hydroxy-3-(piperidin-3-ylmethoxy)-phenyl]-1H-benzoimidazole-5-carboxamidine::CHEMBL303978

SMILES NC(=N)c1cc2[nH]c(nc2cc1F)-c1cccc(OCC2CCCNC2)c1O

InChI Key InChIKey=TYKNBRGVFCIVAT-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50115854   

TargetUrokinase-type plasminogen activator(Human)
Celera

Curated by ChEMBL
LigandPNGBDBM50115854(6-Fluoro-2-[2-hydroxy-3-(piperidin-3-ylmethoxy)-ph...)
Affinity DataKi:  460nMAssay Description:Inhibition of urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Celera

Curated by ChEMBL
LigandPNGBDBM50115854(6-Fluoro-2-[2-hydroxy-3-(piperidin-3-ylmethoxy)-ph...)
Affinity DataKi:  2.10E+4nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Celera

Curated by ChEMBL
LigandPNGBDBM50115854(6-Fluoro-2-[2-hydroxy-3-(piperidin-3-ylmethoxy)-ph...)
Affinity DataKi:  5.00E+4nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Celera

Curated by ChEMBL
LigandPNGBDBM50115854(6-Fluoro-2-[2-hydroxy-3-(piperidin-3-ylmethoxy)-ph...)
Affinity DataKi:  1.25E+5nMAssay Description:Inhibition of Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Celera

Curated by ChEMBL
LigandPNGBDBM50115854(6-Fluoro-2-[2-hydroxy-3-(piperidin-3-ylmethoxy)-ph...)
Affinity DataKi:  2.63E+5nMAssay Description:Inhibition of tissue-type plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed