BDBM50116181 (S)-2-[(1'-Acetyl-2',3',5',6'-tetrahydro-1'H-[3,4']bipyridinyl-4'-carbonyl)-amino]-3-(2'-methoxy-biphenyl-4-yl)-propionic acid::CHEMBL304150

SMILES COc1ccccc1-c1ccc(C[C@H](NC(=O)C2(CCN(CC2)C(C)=O)c2cccnc2)C(O)=O)cc1

InChI Key InChIKey=VGUXHZDVUZBCSL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50116181   

TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50116181((S)-2-[(1'-Acetyl-2',3',5',6'-tetrahydro-1'H-[3,4'...)
Affinity DataIC50: 30nMAssay Description:Inhibition of alpha4-beta7 integrin binding to radiolabeled vascular cell adhesion molecule-1 (VCAM-1) Ig fusion protein in human Jurkat cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed