BDBM50116197 CHEMBL3612358

SMILES CN1CCC[C@H]1c1ccc[n+](CCCCCNCC2CCc3ccc(O)cc3O2)c1

InChI Key InChIKey=DTUYFIYHCUBCJI-UHFFFAOYSA-O

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50116197   

TargetD(3) dopamine receptor(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50116197(CHEMBL3612358)
Affinity DataKi:  43nMAssay Description:Displacement of [3H]raclopride from dopamine D3 receptor (unknown origin) expressed in HEK293 cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2016
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50116197(CHEMBL3612358)
Affinity DataKi:  120nMAssay Description:Displacement of [3H]raclopride from dopamine D2 receptor in Sprague-Dawley rat striatal membranes after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2016
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50116197(CHEMBL3612358)
Affinity DataIC50: 200nMAssay Description:Antagonist activity at human alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of acetylcholine-induced inward current at holding po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2016
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50116197(CHEMBL3612358)
Affinity DataKi:  1.10E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR in Sprague-Dawley rat hippocampus membrane homogenates by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2016
Entry Details Article
PubMed