BDBM50116213 4-((S)-2-Azetidin-2-yl-ethoxy)-7-chloro-2-oxo-3-(3,4,5-trimethyl-phenyl)-1,2-dihydro-quinoline-6-carboxylic acid pyrimidin-2-ylamide::CHEMBL71561

SMILES Cc1cc(-c2c(OCC[C@@H]3CCN3)c3cc(C(=O)Nc4ncccn4)c(Cl)cc3[nH]c2=O)cc(C)c1C

InChI Key InChIKey=DBDBBVLTWXUUQH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50116213   

TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50116213BDBM50116213(4-((S)-2-Azetidin-2-yl-ethoxy)-7-chloro-2-oxo-3-(3...)
Affinity DataIC50: 0.440nMAssay Description:Ability of compound to inhibit [125I-Tyr5,DLeu6,NMeLeu7,Pro9-NEt]GnRH agonist binding to the cloned human Gonadotropin-releasing hormone receptor was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50116213BDBM50116213(4-((S)-2-Azetidin-2-yl-ethoxy)-7-chloro-2-oxo-3-(3...)
Affinity DataIC50: 4nMAssay Description:Ability of compound to inhibit [125I-Tyr5,DLeu6,NMeLeu7,Pro9-NEt]GnRH agonist binding to the rat Gonadotropin-releasing hormone receptor was evaluate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed