BDBM50116237 6-Benzo[1,3]dioxol-5-yl-3-[(benzyl-methyl-amino)-methyl]-8-(2-fluoro-benzyl)-2-(4-methoxy-phenyl)-7-methyl-8H-imidazo[1,2-a]pyrimidin-5-one::CHEMBL306431

SMILES COc1ccc(cc1)-c1nc2n(Cc3ccccc3F)c(C)c(-c3ccc4OCOc4c3)c(=O)n2c1CN(C)Cc1ccccc1

InChI Key InChIKey=UEQIOCUCOGQZDQ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50116237   

TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50116237(6-Benzo[1,3]dioxol-5-yl-3-[(benzyl-methyl-amino)-m...)
Affinity DataKi:  47nMAssay Description:Compound was evaluated in cloned rat Gonadotropin-releasing hormone receptor assay for its ability to displace the binding of [125 I-Tyr, DLeu, NMeLe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50116237(6-Benzo[1,3]dioxol-5-yl-3-[(benzyl-methyl-amino)-m...)
Affinity DataKi:  47nMAssay Description:Inhibition of GnRH receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed