BDBM50116896 CHEMBL3613032

SMILES CC(=O)Oc1ccc(\C=C\C(=O)OCCCCCc2cnnn2CCCO)cc1OC(C)=O

InChI Key InChIKey=BHVNKPFNLGYRLV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50116896   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50116896(CHEMBL3613032)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human 5-LOX expressed in Escherichia coli Bl21 (DE3) assessed as reduction in LTB4 and 5-H(P)ETE) formation pre-incubated for 10 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50116896(CHEMBL3613032)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of 5-LOX in human neutrophils assessed as reduction in LTB4 and 5-H(P)ETE) formation pre-incubated for 15 mins before A23187 and arachidon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMed