BDBM50117328 4-{7-[3-(3,3-Difluoro-piperidin-1-yl)-propoxy]-6-methoxy-quinazolin-4-yl}-piperazine-1-carboxylic acid (4-isopropoxy-phenyl)-amide::CHEMBL125431

SMILES COc1cc2c(ncnc2cc1OCCCN1CCCC(F)(F)C1)N1CCN(CC1)C(=O)Nc1ccc(OC(C)C)cc1

InChI Key InChIKey=IFWXSBLDRFMUHB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50117328   

TargetPlatelet-derived growth factor receptor beta(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50117328(4-{7-[3-(3,3-Difluoro-piperidin-1-yl)-propoxy]-6-m...)
Affinity DataIC50: 29nMAssay Description:Inhibition of wild type Platelet-derived growth factor receptor beta phosphorylation in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50117328(4-{7-[3-(3,3-Difluoro-piperidin-1-yl)-propoxy]-6-m...)
Affinity DataIC50: 150nMAssay Description:Inhibition of platelet derived growth factor receptor beta phosphorylation in MG63 cells in the presence of human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed