BDBM50117381 4-{6-Methoxy-7-[3-(2-methyl-propane-1-sulfonyl)-propoxy]-quinazolin-4-yl}-piperazine-1-carboxylic acid (4-isopropoxy-phenyl)-amide::CHEMBL59735

SMILES COc1cc2c(ncnc2cc1OCCCS(=O)(=O)CC(C)C)N1CCN(CC1)C(=O)Nc1ccc(OC(C)C)cc1

InChI Key InChIKey=KYKHCOJWGFWADS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50117381   

TargetPlatelet-derived growth factor receptor beta(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50117381(4-{6-Methoxy-7-[3-(2-methyl-propane-1-sulfonyl)-pr...)
Affinity DataIC50: 36nMAssay Description:Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50117381(4-{6-Methoxy-7-[3-(2-methyl-propane-1-sulfonyl)-pr...)
Affinity DataIC50: 121nMAssay Description:Inhibition of platelet derived growth factor receptor beta phosphorylation in MG63 cells in the presence of human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed