BDBM50117557 8-Trifluoromethyl-2,3,3a,9b-tetrahydro-1H-cyclopenta[c]quinolin-4-ylamine::CHEMBL313001

SMILES NC1=Nc2ccc(cc2[C@H]2CCC[C@@H]12)C(F)(F)F

InChI Key InChIKey=AINOZXUWKRFZDV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50117557   

TargetNitric oxide synthase, brain(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50117557(8-Trifluoromethyl-2,3,3a,9b-tetrahydro-1H-cyclopen...)
Affinity DataIC50: 1.60E+3nMAssay Description:Concentration required to inhibit neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50117557(8-Trifluoromethyl-2,3,3a,9b-tetrahydro-1H-cyclopen...)
Affinity DataIC50: 5.70E+4nMAssay Description:In vitro inhibition of endothelial nitric oxide synthase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50117557(8-Trifluoromethyl-2,3,3a,9b-tetrahydro-1H-cyclopen...)
Affinity DataIC50: 8.90E+4nMAssay Description:In vitro inhibition of inducible nitric oxide synthase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed