BDBM50118531 CHEMBL135327::Diethyl-carbamic acid 5-phenyl-6-oxa-10,10b-diaza-benzo[e]azulen-4-yl ester

SMILES CCN(CC)C(=O)OC1=C(Oc2cccnc2-n2cccc12)c1ccccc1

InChI Key InChIKey=KWIRXYGAYVTROX-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50118531   

TargetTranslocator protein(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50118531(Diethyl-carbamic acid 5-phenyl-6-oxa-10,10b-diaza-...)
Affinity DataKi:  1.77nMAssay Description:Inhibition of [3H]PK11195 binding to Peripheral type benzodiazepine receptor (PBR) in rat cortex homogenate by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50118531(Diethyl-carbamic acid 5-phenyl-6-oxa-10,10b-diaza-...)
Affinity DataKi:  11nMAssay Description:Inhibition of [3H]PK11195 binding to mitochondrial rat testis Peripheral type benzodiazepine receptor (PBR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50118531(Diethyl-carbamic acid 5-phenyl-6-oxa-10,10b-diaza-...)
Affinity DataKi:  22nMAssay Description:Inhibition of [3H]Ro-5-4864 binding to mitochondrial rat testis Peripheral type benzodiazepine receptor (PBR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed