BDBM50118551 CHEMBL137392::Sulfamic acid 2-tert-butyl-4-oxo-4H-chromen-6-yl ester

SMILES CC(C)(C)c1cc(=O)c2cc(OS(N)(=O)=O)ccc2o1

InChI Key InChIKey=PGFMBHKYSULPEO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50118551   

TargetSteryl-sulfatase(Human)
Novartis Research Institute Vienna

Curated by ChEMBL
LigandPNGBDBM50118551(Sulfamic acid 2-tert-butyl-4-oxo-4H-chromen-6-yl e...)
Affinity DataIC50: 22nMAssay Description:Inhibitory activity against purified human steroid sulfatase (STS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Novartis Research Institute Vienna

Curated by ChEMBL
LigandPNGBDBM50118551(Sulfamic acid 2-tert-butyl-4-oxo-4H-chromen-6-yl e...)
Affinity DataIC50: 22nMAssay Description:Inhibition of steroid sulfataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
Novartis Research Institute Vienna

Curated by ChEMBL
LigandPNGBDBM50118551(Sulfamic acid 2-tert-butyl-4-oxo-4H-chromen-6-yl e...)
Affinity DataIC50: 0.0470nMAssay Description:Inhibition of human sulfatase using 4-methylumbelliferyl sulfate as substrate after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed