BDBM50118664 5-{3-[2-Methoxy-5-(5-trifluoromethyl-tetrazol-1-yl)-phenyl]-6-phenyl-1-oxa-7-aza-spiro[4.5]dec-7-ylmethyl}-2,4-dihydro-[1,2,4]triazol-3-one::CHEMBL316141

SMILES COc1ccc(cc1[C@H]1COC2(C1)CCCN(Cc1n[nH]c(=O)[nH]1)C2c1ccccc1)-n1nnnc1C(F)(F)F

InChI Key InChIKey=LSRPAIIWDVLKSE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50118664   

TargetSubstance-P receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50118664(5-{3-[2-Methoxy-5-(5-trifluoromethyl-tetrazol-1-yl...)
Affinity DataIC50: 0.100nMAssay Description:Displacement of [125I]-labeled substance P from the cloned human Tachykinin receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed