BDBM50118698 6-(3-Fluoro-phenyl)-4,4-dimethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one::CHEMBL138005

SMILES CC1(C)OC(=O)Nc2ccc(cc12)-c1cccc(F)c1

InChI Key InChIKey=RRSKDZKYPQSTFG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50118698   

TargetProgesterone receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118698(6-(3-Fluoro-phenyl)-4,4-dimethyl-1,4-dihydro-benzo...)
Affinity DataIC50: 3.80nMAssay Description:Antagonist activity against progesterone receptor (PR) in an assay using PRE-luciferase plasmid co-transfected CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118698(6-(3-Fluoro-phenyl)-4,4-dimethyl-1,4-dihydro-benzo...)
Affinity DataIC50: 8.20nMAssay Description:Antagonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed