BDBM50118794 2-(Oxalyl-amino)-6-pyridin-3-ylmethyl-4,5,6,7-tetrahydro-thieno[2,3-c]pyridine-3-carboxylic acid::CHEMBL140757

SMILES OC(=O)C(=O)Nc1sc2CN(Cc3cccnc3)CCc2c1C(O)=O

InChI Key InChIKey=CPBBXECXUZCULL-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50118794   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50118794(2-(Oxalyl-amino)-6-pyridin-3-ylmethyl-4,5,6,7-tetr...)
Affinity DataKi:  900nMpH: 5.5Assay Description:Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50118794(2-(Oxalyl-amino)-6-pyridin-3-ylmethyl-4,5,6,7-tetr...)
Affinity DataKi:  1.20E+4nMAssay Description:Inhibition of human recombinant Protein-tyrosine phosphatase 1B.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed