BDBM50118858 4-(6,7-Dimethoxy-quinazolin-4-yl)-2-methyl-piperazine-1-carboxylic acid (4-phenoxy-phenyl)-amide::CHEMBL343133

SMILES COc1cc2ncnc(N3CCN(C(C)C3)C(=O)Nc3ccc(Oc4ccccc4)cc3)c2cc1OC

InChI Key InChIKey=OSYWVHQKLCIONH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50118858   

TargetPlatelet-derived growth factor receptor alpha/beta(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50118858(4-(6,7-Dimethoxy-quinazolin-4-yl)-2-methyl-piperaz...)
Affinity DataIC50: 80nMAssay Description:Concentration required for 50% inhibition against autophosphorylation of Platelet-derived growth factor receptor beta in intact cells using a two sit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed