BDBM50118869 4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-carboxylic acid 4-tert-butyl-benzylamide::CHEMBL336005

SMILES COc1cc2ncnc(N3CCN(CC3)C(=O)NCc3ccc(cc3)C(C)(C)C)c2cc1OC

InChI Key InChIKey=XBRIIWVCRRXRPA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50118869   

TargetPlatelet-derived growth factor receptor alpha/beta(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50118869(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)
Affinity DataIC50: 110nMAssay Description:Concentration required for 50% inhibition against autophosphorylation of Platelet-derived growth factor receptor beta in intact cells using a two sit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed