BDBM50119027 (E)-3-(4-Fluoro-2,6-dimethyl-phenyl)-N-(3-methoxy-4-oxazol-5-yl-phenyl)-acrylamide::CHEMBL314330

SMILES COc1cc(NC(=O)\C=C\c2c(C)cc(F)cc2C)ccc1-c1cnco1

InChI Key InChIKey=LIYMSZSRLVPVSH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50119027   

TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Bristol-Myers Squibb Pri

Curated by ChEMBL
LigandPNGBDBM50119027((E)-3-(4-Fluoro-2,6-dimethyl-phenyl)-N-(3-methoxy-...)
Affinity DataIC50: 75nMAssay Description:Inhibitory activity of compound was evaluated against the inosine monophosphate dehydrogenase -II (IMPDH-II) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed