BDBM50119073 4-(3-Ethynyl-phenylamino)-6,7-bis-(2-methoxy-ethoxy)-quinoline-3-carbonitrile::CHEMBL95320

SMILES COCCOc1cc2ncc(C#N)c(Nc3cccc(c3)C#C)c2cc1OCCOC

InChI Key InChIKey=PNKFULCCPOFCJC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50119073   

TargetEpidermal growth factor receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50119073(4-(3-Ethynyl-phenylamino)-6,7-bis-(2-methoxy-ethox...)
Affinity DataIC50: 850nMAssay Description:Inhibition of Epidermal Growth Factor Receptor (EGFR) autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50119073(4-(3-Ethynyl-phenylamino)-6,7-bis-(2-methoxy-ethox...)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of human epidermal growth factor receptor-2 autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed