BDBM50119078 (1R,6S,8S,8aS)-6-Amino-6-benzyl-1-ethyl-8-methoxy-5-oxo-octahydro-indolizine-3-carboxylic acid 4-carbamimidoyl-benzylamide; hydrochloride::CHEMBL542435

SMILES CC[C@@H]1CC(N2[C@@H]1[C@H](C[C@@](N)(Cc1ccccc1)C2=O)OC)C(=O)NCc1ccc(cc1)C(N)=N

InChI Key InChIKey=STQIXRRUFSZYLF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50119078   

TargetProthrombin(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50119078((1R,6S,8S,8aS)-6-Amino-6-benzyl-1-ethyl-8-methoxy-...)
Affinity DataIC50: 210nMAssay Description:Compound was tested for inhibitory activity against ThrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50119078((1R,6S,8S,8aS)-6-Amino-6-benzyl-1-ethyl-8-methoxy-...)
Affinity DataIC50: 420nMAssay Description:Compound was tested for inhibitory activity against Coagulation factor VIIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetPlasminogen(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50119078((1R,6S,8S,8aS)-6-Amino-6-benzyl-1-ethyl-8-methoxy-...)
Affinity DataIC50: 1.10E+4nMAssay Description:Compound was tested for inhibitory activity against PlasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50119078((1R,6S,8S,8aS)-6-Amino-6-benzyl-1-ethyl-8-methoxy-...)
Affinity DataIC50: 1.33E+5nMAssay Description:Compound was tested for inhibitory activity against Coagulation factor XIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed