BDBM50119079 (6R,8aS)-6-Benzyl-6-hydroxy-5-oxo-octahydro-indolizine-3-carboxylic acid 4-carbamimidoyl-benzylamide; hydrochloride::CHEMBL544560

SMILES NC(=N)c1ccc(CNC(=O)C2CC[C@H]3CC[C@@](O)(Cc4ccccc4)C(=O)N23)cc1

InChI Key InChIKey=PVTGBPNXHBYAJX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50119079   

TargetProthrombin(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50119079((6R,8aS)-6-Benzyl-6-hydroxy-5-oxo-octahydro-indoli...)
Affinity DataIC50: 20nMAssay Description:Compound was tested for inhibitory activity against ThrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50119079((6R,8aS)-6-Benzyl-6-hydroxy-5-oxo-octahydro-indoli...)
Affinity DataIC50: 20nMAssay Description:Compound was tested for inhibitory activity against ThrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50119079((6R,8aS)-6-Benzyl-6-hydroxy-5-oxo-octahydro-indoli...)
Affinity DataIC50: 1.10E+3nMAssay Description:Compound was tested for inhibitory activity against Coagulation factor VIIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed