BDBM50119176 1-Hexyl-3-[4-(4-{[(S)-2-hydroxy-3-(4-hydroxy-phenoxy)-propylamino]-methyl}-piperidine-1-sulfonyl)-phenyl]-urea::CHEMBL430662

SMILES CCCCCCNC(=O)Nc1ccc(cc1)S(=O)(=O)N1CCC(CNC[C@H](O)COc2ccc(O)cc2)CC1

InChI Key InChIKey=OFYUUXIYRPQSFG-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50119176   

TargetBeta-1 adrenergic receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50119176(1-Hexyl-3-[4-(4-{[(S)-2-hydroxy-3-(4-hydroxy-pheno...)
Affinity DataEC50:  1.09E+4nMAssay Description:In vitro agonist activity measured by increase in cAMP levels in chinese hamster ovary cells (CHO) cells expressing human Beta-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50119176(1-Hexyl-3-[4-(4-{[(S)-2-hydroxy-3-(4-hydroxy-pheno...)
Affinity DataEC50:  58nMAssay Description:In vitro agonist activity measured by increase in cAMP levels in chinese hamster ovary cells (CHO) cells expressing human Beta-3 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed