BDBM50119185 1-[4-(4-{[(S)-2-Hydroxy-3-(8-hydroxy-2-oxo-1,2,3,4-tetrahydro-quinolin-5-yloxy)-propylamino]-methyl}-piperidine-1-sulfonyl)-phenyl]-3-octyl-urea::CHEMBL327519

SMILES CCCCCCCCNC(=O)Nc1ccc(cc1)S(=O)(=O)N1CCC(CNC[C@H](O)COc2ccc(O)c3NC(=O)CCc23)CC1

InChI Key InChIKey=SRQIEPXVDNZHRF-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50119185   

TargetBeta-3 adrenergic receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50119185(1-[4-(4-{[(S)-2-Hydroxy-3-(8-hydroxy-2-oxo-1,2,3,4...)
Affinity DataEC50:  5nMAssay Description:In vitro agonist activity measured by increase in cAMP levels in chinese hamster ovary cells (CHO) cells expressing human Beta-3 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50119185(1-[4-(4-{[(S)-2-Hydroxy-3-(8-hydroxy-2-oxo-1,2,3,4...)
Affinity DataEC50:  390nMAssay Description:In vitro agonist activity measured by increase in cAMP levels in chinese hamster ovary cells (CHO) cells expressing human Beta-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50119185(1-[4-(4-{[(S)-2-Hydroxy-3-(8-hydroxy-2-oxo-1,2,3,4...)
Affinity DataEC50:  680nMAssay Description:In vitro agonist activity measured by increase in cAMP levels in chinese hamster ovary cells (CHO) cells expressing human Beta-2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed