BDBM50119186 1-(9H-Carbazol-4-yloxy)-3-{[1-(3,3,3-trifluoro-propyl)-piperidin-4-ylmethyl]-amino}-propan-2-ol::CHEMBL103137

SMILES O[C@@H](CNCC1CCN(CCC(F)(F)F)CC1)COc1cccc2[nH]c3ccccc3c12

InChI Key InChIKey=KYEXTNNLWDSEAZ-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50119186   

TargetBeta-2 adrenergic receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50119186(1-(9H-Carbazol-4-yloxy)-3-{[1-(3,3,3-trifluoro-pro...)
Affinity DataEC50: >1.00E+3nMAssay Description:In vitro agonist activity measured by increase in cAMP levels in chinese hamster ovary cells (CHO) cells expressing human Beta-2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50119186(1-(9H-Carbazol-4-yloxy)-3-{[1-(3,3,3-trifluoro-pro...)
Affinity DataEC50:  187nMAssay Description:In vitro agonist activity measured by increase in cAMP levels in chinese hamster ovary cells (CHO) cells expressing human Beta-3 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50119186(1-(9H-Carbazol-4-yloxy)-3-{[1-(3,3,3-trifluoro-pro...)
Affinity DataEC50:  417nMAssay Description:In vitro agonist activity measured by increase in cAMP levels in chinese hamster ovary cells (CHO) cells expressing human Beta-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed