BDBM50119208 4-Methyl-2-[2-(4-phenoxy-phenoxy)-acetylamino]-pentanoic acid (2-hydroxy-5-oxo-tetrahydro-furan-3-yl)-amide::CHEMBL102154

SMILES CC(C)C[C@H](NC(=O)COc1ccc(Oc2ccccc2)cc1)C(=O)N[C@H]1CC(=O)OC1O

InChI Key InChIKey=YPDLHOCWYZLMQS-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50119208   

TargetCaspase-6(Human)
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119208(4-Methyl-2-[2-(4-phenoxy-phenoxy)-acetylamino]-pen...)
Affinity DataIC50: 2.12E+4nMAssay Description:Inhibitory concentration required against caspase-6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119208(4-Methyl-2-[2-(4-phenoxy-phenoxy)-acetylamino]-pen...)
Affinity DataIC50: 545nMAssay Description:Inhibitory concentration against caspase-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119208(4-Methyl-2-[2-(4-phenoxy-phenoxy)-acetylamino]-pen...)
Affinity DataIC50: 2.21E+3nMAssay Description:Inhibition of caspase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119208(4-Methyl-2-[2-(4-phenoxy-phenoxy)-acetylamino]-pen...)
Affinity DataIC50: 6.82E+3nMAssay Description:Inhibitory concentration against caspase-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-8(Human)
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119208(4-Methyl-2-[2-(4-phenoxy-phenoxy)-acetylamino]-pen...)
Affinity DataIC50: 9.28E+3nMAssay Description:Inhibitory concentration against caspase-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed