BDBM50119214 2-[2-(4-Methoxy-naphthalen-1-yloxy)-acetylamino]-4-methyl-pentanoic acid (2-hydroxy-5-oxo-tetrahydro-furan-3-yl)-amide::CHEMBL100114

SMILES COc1ccc(OCC(=O)N[C@@H](CC(C)C)C(=O)N[C@H]2CC(=O)OC2O)c2ccccc12

InChI Key InChIKey=XXQCRRRNRLLOKC-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50119214   

TargetCaspase-6(Human)
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119214(2-[2-(4-Methoxy-naphthalen-1-yloxy)-acetylamino]-4...)
Affinity DataIC50: 2.26E+4nMAssay Description:Inhibitory concentration required against caspase-6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119214(2-[2-(4-Methoxy-naphthalen-1-yloxy)-acetylamino]-4...)
Affinity DataIC50: 4.08E+3nMAssay Description:Inhibitory concentration against caspase-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119214(2-[2-(4-Methoxy-naphthalen-1-yloxy)-acetylamino]-4...)
Affinity DataIC50: 831nMAssay Description:Inhibition of caspase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-8(Human)
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119214(2-[2-(4-Methoxy-naphthalen-1-yloxy)-acetylamino]-4...)
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibitory concentration against caspase-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119214(2-[2-(4-Methoxy-naphthalen-1-yloxy)-acetylamino]-4...)
Affinity DataIC50: 263nMAssay Description:Inhibitory concentration against caspase-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed