BDBM50119256 2-{[1-(2-Hydroxy-5-oxo-tetrahydro-furan-3-ylcarbamoyl)-propylcarbamoyl]-methoxy}-naphthalene-1-carboxylic acid::CHEMBL327298

SMILES CC(C)C(NC(=O)COc1ccc2ccccc2c1C(O)=O)C(=O)N[C@H]1CC(=O)OC1O

InChI Key InChIKey=ASGHIPSJIOETFI-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50119256   

TargetCaspase-3(Human)
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119256(2-{[1-(2-Hydroxy-5-oxo-tetrahydro-furan-3-ylcarbam...)
Affinity DataIC50: 401nMAssay Description:Inhibition of Caspase-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-8(Human)
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119256(2-{[1-(2-Hydroxy-5-oxo-tetrahydro-furan-3-ylcarbam...)
Affinity DataIC50: 733nMAssay Description:Inhibition of Caspase-8 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119256(2-{[1-(2-Hydroxy-5-oxo-tetrahydro-furan-3-ylcarbam...)
Affinity DataIC50: 2.96E+3nMAssay Description:Inhibition of Caspase-1 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-6(Human)
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119256(2-{[1-(2-Hydroxy-5-oxo-tetrahydro-furan-3-ylcarbam...)
Affinity DataIC50: 3.61E+3nMAssay Description:Inhibition of Caspase-6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119256(2-{[1-(2-Hydroxy-5-oxo-tetrahydro-furan-3-ylcarbam...)
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of Caspase-7 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed