BDBM50119258 CHEMBL323322::N-(2-Hydroxy-5-oxo-tetrahydro-furan-3-yl)-2-[2-(naphthalen-1-ylamino)-acetylamino]-butyramide

SMILES CC(C)C(NC(=O)CNc1cccc2ccccc12)C(=O)N[C@H]1CC(=O)OC1O

InChI Key InChIKey=ZYWFKPCNVPPHDB-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50119258   

TargetCaspase-1(Human)
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119258(N-(2-Hydroxy-5-oxo-tetrahydro-furan-3-yl)-2-[2-(na...)
Affinity DataIC50: 15nMAssay Description:Inhibition of Caspase-1 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-8(Human)
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119258(N-(2-Hydroxy-5-oxo-tetrahydro-furan-3-yl)-2-[2-(na...)
Affinity DataIC50: 450nMAssay Description:Inhibition of Caspase-8 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119258(N-(2-Hydroxy-5-oxo-tetrahydro-furan-3-yl)-2-[2-(na...)
Affinity DataIC50: 1.55E+3nMAssay Description:Inhibition of Caspase-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119258(N-(2-Hydroxy-5-oxo-tetrahydro-furan-3-yl)-2-[2-(na...)
Affinity DataIC50: 6.14E+3nMAssay Description:Inhibition of Caspase-7 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-6(Human)
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119258(N-(2-Hydroxy-5-oxo-tetrahydro-furan-3-yl)-2-[2-(na...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of Caspase-6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed