BDBM50119266 1-{[1-(2-Hydroxy-5-oxo-tetrahydro-furan-3-ylcarbamoyl)-propylcarbamoyl]-methoxy}-naphthalene-2-carboxylic acid::CHEMBL101145

SMILES CC(C)C(NC(=O)COc1c(ccc2ccccc12)C(O)=O)C(=O)N[C@H]1CC(=O)OC1O

InChI Key InChIKey=AOUFLZQXBYFGOZ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50119266   

TargetCaspase-8(Human)
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119266(1-{[1-(2-Hydroxy-5-oxo-tetrahydro-furan-3-ylcarbam...)
Affinity DataIC50: 48nMAssay Description:Inhibition of Caspase-8 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119266(1-{[1-(2-Hydroxy-5-oxo-tetrahydro-furan-3-ylcarbam...)
Affinity DataIC50: 54nMAssay Description:Inhibition of Caspase-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119266(1-{[1-(2-Hydroxy-5-oxo-tetrahydro-furan-3-ylcarbam...)
Affinity DataIC50: 385nMAssay Description:Inhibition of Caspase-1 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-6(Human)
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119266(1-{[1-(2-Hydroxy-5-oxo-tetrahydro-furan-3-ylcarbam...)
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of Caspase-6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Idun Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119266(1-{[1-(2-Hydroxy-5-oxo-tetrahydro-furan-3-ylcarbam...)
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of Caspase-7 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed